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  6. Tohoku Univ. Technology:Non-enzymatic biosensor:T22-321

Tohoku Univ. Technology:Non-enzymatic biosensor:T22-321

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last updated:Sep 26, 2023

Tohoku Techno Arch Co., Ltd.
Tohoku Techno Arch Co., Ltd.
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Organic electrochemical device that can be manufactured by the entire printing process

When an organic electrochemical transistor (OECT) is modified with an enzyme such as glucose oxidase, it can be applied to a biosensor capable of detecting a sugar such as a blood sugar-level. The development of a non-enzymatic OECT biosensor has been promoted because of the instability and high price of enzymes. In the non-enzymatic OECT biosensor, phenylboronic acid (PBA), a glucose-sensing functional moiety, is generally used instead of enzymes. However, the electropolymerization reaction is essential for the application of PBA, and the complicated manufacturing process has been a problem.   The present invention relates to a glucose sensor that does not use an enzyme or PBA. The glucose sensor is driven by using a membrane containing a polysaccharide mixed with a conductive polymer as a glucose sensing site. The simplicity of the manufacturing process is also a major advantage because the entire process can be produced by printing if various metal inks are used as electrodes. The figure shows the result of measuring a glucose solution using the sensor. It can be seen that the low concentration of glucose can be detected without using enzyme or PBA.

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T22-321_1.png

Tohoku Univ. Technology:Non-enzymatic biosensor:T22-321

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T22-321_1.png
  • Related Link - https://www.t-technoarch.co.jp/anken.php

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Tohoku Univ. Technology : Non-enzymatic biosensor : T22-321

Tohoku Univ. Technology : Non-enzymatic biosensor : T22-321

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The revenue generated from technology transfer is reinvested into universities and researchers as new research funding, which is used to create further research outcomes. To ensure the smooth operation of this cycle, known as the "Intellectual Creation Cycle," we will actively promote technology transfer. The types of seeds we handle include patents, know-how, databases, and programs. We have established a collaborative framework by concluding basic technology transfer agreements with the following universities (as of June 1, 2025): - Tohoku University - Hirosaki University - Iwate University - Akita University - Fukushima University - Yamagata University - Tohoku Gakuin University - Iwate Medical University - Fukushima Medical University - Aizu University - Miyagi University - Hokkaido University - Muroran Institute of Technology - Showa Medical University

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