Book "Bioreactors for Cultivating Microorganisms, Animal/Plant Cells"

A detailed explanation of technical strategies to avoid failures in the design and scale-up of bioreactors, including an Excel template with examples of design and scale-up calculations.

This book is about the design and scale-up of industrial-scale bioreactors, where information tends to be limited. It details business strategies for cost optimization and technical strategies to avoid failures in scale-up. Covering everything from the basics of bioreactors to comparisons of bioreactors in animal cell/microorganism cultures, the advantages and disadvantages of various operations, and scale-up troubles, it encompasses both foundational knowledge and practical applications. Along with practical exercises using examples of design and scale-up calculations in Excel included, this book is intended for practical use. **Features of this book:** ➢ Business strategies for optimizing costs in the design of industrial-scale bioreactors ➢ Detailed descriptions of fed-batch and perfusion culture operations for high-density cultivation, which have gained attention in recent years ➢ Learning the reaction rates of microorganisms from the basics to design bioreactors ➢ Detailed introduction of technical strategies to avoid failures in the design and scale-up of bioreactors ➢ Comparison of animal cell culture bioreactors and microorganism culture bioreactors ➢ Summary of the advantages and disadvantages of batch, continuous, and semi-batch (fed-batch) operations ➢ Excel templates for all 48 calculation problems related to bioreactors included

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