PAT inline particle size, turbidity, and polymorphism monitoring device

basic information

- Blaze's patented single optical path technology allows multiple analytical techniques to utilize the same optical path simultaneously, enabling multiple measurements with a single probe. - The installation requires only one port, reducing setup time and maintenance while building a robust system. - With a single probe, the effects of baffle plate and heat sink from the probe can be minimized. - Integrating multiple measurement techniques enhances information. For example, explaining the particle size distribution (CLD) trend obtained from images with microscope images, correcting Raman intensity (Y-axis) using Blaze HDR turbidity to improve transition identification, and verifying the cleanliness of windows with microscope images. - With a single probe for multiple measurements, it is possible to measure small sample flow synthesis, etc. - By combining with microscope images, accurate information is obtained for determining material conditions, measurement zones, fouling (adhesion to inner walls, etc.), particle shapes, multiphase, polymorphism, etc. - Accurate information accelerates decision-making and shortens process development time. Understanding of the process improves more quickly, leading to a reduction in the number of experiments. - Total cost reduction: reduction in installation costs, operating costs, and maintenance costs.

Price information

The price varies depending on the contents of the options.

Delivery Time

Applications/Examples of results

Application Examples 1) Fine Particle Related - Optimization of reaction processes (Raman) - Examination of crystallization process conditions - Examination and management of formulation processes (granulation, milling) - Examination of API dissolution - Checking the mixing degree, segregation degree, and agglomeration degree of powders - Particle size management of slurries in battery manufacturing processes - Management of droplet size in emulsions 2) Coarse Particle Related - Monitoring of cells in bioreactors - Monitoring of clarity - Detection of foreign substances - Monitoring of protein aggregation

Detailed information

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  According to FRBM's assumptions, let's stop process management. With Blazematrics, you can accurately grasp the state of particles. The FDA paper states that FRBM is inaccurate.

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  You can choose from a variety of options to meet your needs.