We are continuously developing new products while also focusing on the collection of safety data!
We are seeking research ideas for nasal mucosa studies using animal models. Currently, we are employing a method where a tube is inserted through either the right or left nasal cavity of rodent animal models to deliver a solution, while creating negative pressure in the opposite nasal cavity to collect the liquid. However, it seems that rodents, which cannot breathe through their mouths, are prone to having the liquid that enters through their noses easily reach their lungs. This leads to weakness during continuous washing, making it difficult to evaluate safety for long-term use. Therefore, we have decided to seek solutions to this issue from researchers across a wide range of fields working with animal models. If you have research ideas using animal models that can evaluate the safety of nasal irrigation products during continuous washing, please submit your proposals through the Innovation Portal linked below. *For more details, please refer to the PDF document or feel free to contact us.
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【Desired Technology】 ■Ability to evaluate the safety of nasal irrigation products during continuous washing in vivo ・Assuming more than 21 washings (3 times/day × 7 days) ・Preferably using rodents due to the abundance of back data on nasal mucosa ・Also considering monkeys and dogs, but small animals that are easier to handle are preferred ・As long as they can reproduce the nasal cavity environment, nasal epithelial cells or mucosal cells cultured in layers, even if not in vivo, are acceptable ＜Technologies Not Applicable＞ ■Technologies evaluated through in vitro or human clinical trials ＜Expected Partners＞ ■Researchers in the field of nasal mucosa and allergies who work with animal models ■Researchers skilled in creating and utilizing animal models ■Researchers in alternative methods to animal testing *For more details, please refer to the PDF document or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.
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Our company, yet2com, is an expert in linking open innovation (OI) to corporate innovation in line with our clients' business growth strategies. Founded in 1999 in Boston, USA (yet2.com Inc.), we have been providing OI services to manufacturers around the world for over 20 years. We have a proven track record of over 10 years in conducting technology research for not only corporate clients but also U.S. government agencies. With our solid services and methodologies, we lead client companies to successful open innovation. If you are wondering what kind of research is progressing in this technological field, whether there are materials with specific characteristics, or if there are alternative uses for newly developed materials for a particular purpose, please feel free to contact us.