"Composite catalysts" that assist in the efficient synthesis of high value-added substances [Shinshu University]

Easily synthesized from commercially available materials! Successfully obtained oxazolidinone with good yield under mild conditions.

We will introduce the results of the development of a new acid catalyst aimed at the efficient synthesis of "cyclic carbonate," used in electrolytes for lithium-ion batteries, and "oxazolidinone," which is widely present in pharmaceuticals. Conventional technologies have left challenges such as requiring high-temperature heating and having limited substrate generality. In this context, we successfully used magnesium iodide as a metal salt in reactions employing isocyanates, achieving a good yield of oxazolidinone under mild conditions at 35°C. The production and sale of this catalyst, aimed at applications in the manufacturing processes of organic materials and pharmaceuticals, are anticipated. 【Conventional Technology and Challenges】 ■ There are relatively few reports of reactions involving the mild reaction of carbon dioxide at atmospheric pressure through the simple operation of adding ligands to commercially available metal salts. ■ Requires high-temperature heating. ■ Limited substrate generality. *For more details, please refer to the PDF document or feel free to contact us.

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