JAPAN PHARMA CO.,LTD List of Products and Services

GrantriaⓇ is an inner beauty ingredient that combines three effective components (ellagic acid, punicalagin, and punicic acid) found in pomegranates in a unique ratio to deliver noticeable effects. Thanks to Zeus Hygia's proprietary ADOP Technology, we have successfully encapsulated the whole pomegranate seed oil and water-soluble extract, simultaneously incorporating three components that combat oxidative stress. In a study involving 80 women aged 35 to 65, those who took 300 mg of GrantriaⓇ daily for 60 days showed significant improvements in crow's feet, forehead wrinkles, skin radiance, and roughness compared to the placebo group. (Am J Transl Res. 16, 8043, 2024) We propose a new skincare approach that includes GrantriaⓇ for drinking care against spots and wrinkles, in addition to daily skincare routines.

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Turmeric (also known as curcumin) is known as a spice for curry, but it has also been widely used in traditional medicine as a gastrointestinal remedy. Its active component, curcumin (curcuminoids), has antioxidant and anti-inflammatory properties, and curcumin is well-known for its functions in protecting the liver and improving fatigue, as well as various other effects such as maintaining cognitive function (Nutrients 2020, 12, 1678) and reducing discomfort in the knee joints (J Orthop Sci (2014) 19:933–939) have been reported (Chem Biol Interact, 174, 27, 2008; Carcinogenesis, 25, 1671, 2004). Biosolve CurcuminⓇ, developed by Zeus Hygia, utilizes a unique encapsulation technology called Biosolve Technology to encapsulate curcumin. This material improves the water dispersibility, absorption, and bioavailability of curcumin. Compared to regular curcumin, it is expected to enhance the antioxidant and anti-inflammatory effects of curcumin, and human trials have confirmed its effectiveness in reducing joint pain.

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Mango is known as a delicious fruit with high nutritional value, but its parts such as seeds, leaves, and bark have also been traditionally used for health purposes since ancient times. The active compound mangiferin found in mango leaves and bark is known for its antioxidant, anti-inflammatory, and immune-modulating effects (Pharmacogn Rev. 4, 42, 2010). StadiceⓇ, developed using Zeus Hygia's proprietary Insolib technology, has successfully stabilized the mangiferin contained in mango bark extract. Its neuroprotective effects through the antioxidant power of mangiferin contribute to maintaining brain health. In a human trial involving 60 healthy participants aged 18 to 45 who engage in e-sports, StadiceⓇ was administered at a dosage of 300mg/day for 7 consecutive days, and various tests were conducted to measure cognitive abilities. Significant improvements were observed in mental speed, concentration, mental attention, and response inhibition compared to before intake (Cureus 16, e65751, 2024).

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We have successfully manufactured the traditional Chinese food "Dou Chi" using our unique fermentation technology and extracted the beneficial component "Dou Chi Extract," which gently regulates blood sugar levels. We are maximizing the functions hidden in this traditional food that has been passed down since ancient times through the power of science. It can be applied to various products such as supplements in capsule or tablet form, cookies, rice crackers, instant miso soup, and other foods. Made with organic certified soybeans. HALAL certified ingredients. It is a long-selling product that has received great acclaim overseas. For more details, please feel free to contact us.

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The male menopause syndrome (LOH syndrome) is known to cause various symptoms due to a decrease in testosterone secretion, with an estimated 6.55 million patients in Japan. In the Japanese pharmaceutical industry, research is being conducted to develop materials that support men dealing with testosterone reduction, leading to the release of the patented material "Steron Power Mix." This is a powdered blend of plant extracts that can be applied to various products, including supplements for middle-aged men and those in the fertility generation. For further details, please feel free to contact us.

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Black tea is one of the classifications of Chinese tea, characterized by microbial fermentation. "Black Tea Extract Powder" is a proprietary ingredient developed based on traditional methods. Its effectiveness has been confirmed in human trials, and it has a track record of functional food notifications, for which we provide application support. It is a powder made from 100% plant extracts without the use of excipients. HALAL certified ingredient. For more details, please feel free to contact us.

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We discovered "Katsuobushi Oligopeptide," which gently leads to an increase in blood pressure through a unique manufacturing method using katsuobushi, a traditional Japanese ingredient, and have commercialized it. We have standardized its angiotensin-converting enzyme inhibitory activity. It can be applied to various products such as supplements in capsule or tablet form, cookies, rice crackers, instant miso soup, and other foods, as well as stick jelly and drinks. It is a long-selling product that has received favorable reviews overseas. For more details, please feel free to contact us.

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