A Low-Shear Platform for Reliable Blood Compatibility Assessment
Hemolysis testing in accordance with standards such as ASTM F1841 evaluates whether blood pumps and circulatory support devices cause excessive red blood cell damage. However, circuit-induced shear stress may confound the assessment of device-related plasma protein damage, particularly von Willebrand factor (VWF) degradation. The system incorporates two features: Volume-adjustable reservoir bags: Compensate for pressure fluctuations during repeated blood sampling to maintain consistent test conditions. A smaller-diameter resistance tube: Provides the required circuit resistance through distributed pressure loss along its length, helping avoid localized shear stress concentrations. Together, these features aim to maintain low shear stress within the test circuit and support reproducible blood compatibility assessments under defined pressure and flow conditions with a small blood volume.
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The revenue generated from technology transfer is reinvested into universities and researchers as new research funding, which is used to create further research outcomes. To ensure the smooth operation of this cycle, known as the "Intellectual Creation Cycle," we will actively promote technology transfer. The types of seeds we handle include patents, know-how, databases, and programs. We have established a collaborative framework by concluding basic technology transfer agreements with the following universities (as of April 1, 2026): - Tohoku University - Hirosaki University - Iwate University - Akita University - Fukushima University - Yamagata University - Tohoku Gakuin University - Iwate Medical University - Fukushima Medical University - Aizu University - Miyagi University - Hokkaido University - Muroran Institute of Technology - Showa Medical University - Asahikawa Medical University





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