【New Product Exhibition Planned!】Announcement of Participation in the 26th Interphex Japan Exhibition

Are you having trouble with "contamination control"? We can eliminate liquid pooling and ensure that cleaning and sterilization can be carried out easily and reliably!

■NDV Dead Space Countermeasure Products These are products designed with a compact structure that eliminates dead spaces (such as pockets and liquid traps) in the valve body. They can be used as "contamination countermeasures" in pharmaceuticals, food, and bioprocesses. 【Are you facing any of these issues?】 ☑ Fluid enters the gaps inside the valve during fluid passage or when closing the valve... ☑ Large dead legs in piping cause issues like liquid traps and ineffective steam sterilization... ☑ You want to review complex piping layouts to eliminate fluid contamination risks... 【Features】 ● Sampling Valve Type P: - Enables fluid sampling without dead space! ● Three-Way Valve Type K: - Allows switching and mixing of flow paths with one body, without dead space! ● Tank Bottom Valve Type T: - A valve specifically for tank bottoms that achieves high stirring efficiency and eliminates residual discharge! ● Self-Drain Type F: - A valve that further enhances the effect of preventing liquid traps! ■ This product will be exhibited at the "26th Interphex Japan." *For more details, please refer to the catalog or feel free to contact us.

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Easy with 90-degree operation! Prevents over-tightening and damage! "I'm worried if it's securely tightened..." We solve this kind of concern.

The "BQL400NB model" is a rapid opening and closing type handle diaphragm valve from BioClean. While the standard handle version requires about 5 turns of operation (for DN50), the rapid opening and closing handle allows for a very simple operation of just "opening and closing by 90 degrees." The valve's open and closed status can be clearly seen from a distance based on the handle position. Additionally, it has achieved a lighter and more compact design compared to conventional products. Please try the easy operation and stable closing performance of the 90-degree rotating lever handle. 【We solve the following problems!】 ■ Excessive opening and closing torque → Reduction is possible, greatly contributing to labor savings. ■ Want to check the opening and closing status from a distance → The valve's open and closed status can be clearly seen from a distance based on the handle position. ■ Damage caused by over-tightening the valve → Only the minimum necessary operation is required. This prevents damage and extends lifespan. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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An evolved version of the bio-clean diaphragm valve. The structure eliminates liquid pooling by positioning the valve shaft horizontally. A solution for dead space!

The self-draining type is a valve body that further enhances the liquid retention prevention effect of the Bio-Clean diaphragm valve series. When this valve is installed on horizontal piping, it is designed to eliminate liquid retention by positioning the valve shaft horizontally. 【Specifications (excerpt)】 ■ Stainless steel body (Applicable nominal diameter (DN): 8 to 100) ■ Lined body (Applicable nominal diameter (DN): 15 to 50) ■ The surface finish classification of the body and diaphragm specifications conform to standard specifications. ■ Various drive components for manual operation valves and air-operated ON-OFF valves can be used interchangeably. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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No dead space (in pockets or liquid traps), fluid sampling is OK. Can be used extensively!!

**Features** - Fluid sampling can be done without dead space (such as in pockets or liquid traps). - It can be directly installed in piping, is compact, and has a structure that prevents fluid residue in the valve. - In addition to sample collection, it can be widely used for branching, merging (mixing), introducing and discharging cleaning water or sterilizing steam. **Specifications (Excerpt)** - Main body material: SUS316L - Applicable nominal diameter (DN): Standard combination of main pipe and valve: 15 to 50 (other ranges available as options) - Operation method: Manual operation and pneumatic operation methods are both applicable. *For more details, please refer to the PDF document or feel free to contact us.*

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No short pipe section and a small dead leg! A compact design sample collection valve.

The "Bio-Clean Diaphragm Valve" is a dedicated valve for sample collection. Since it does not use a cheese fitting, there is no short pipe section, resulting in a smaller dead leg. Additionally, its compact design and lightweight construction reduce the load on the piping. It can be widely used for introducing and discharging branch flows, merging (mixing liquids), cleaning water, and sterilizing steam. 【Features】 ■ Does not use a cheese fitting ■ No short pipe section, resulting in a smaller dead leg ■ Compact installation due to the integrated structure of the main pipe and body ■ Mass reduced by an average of 23% compared to conventional products ■ Reduced load on piping due to lightweight design *For more details, please refer to the materials. Feel free to contact us with any inquiries.

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Diverging, merging, and the introduction and discharge of cleaning water and sterilizing steam are "applicable." The internal shape of the valve has no dead space, making it ideal for preventing liquid accumulation.

**Features** - It can be directly mounted inside the piping, is compact, and has a structure that prevents fluid residue inside the valve. - It can be widely used for applications such as branching, merging (mixing liquids), introducing and discharging cleaning water or sterilizing steam. **Specifications (Excerpt)** - Main body material: SUS316L - Applicable nominal diameter (DN): Standard combination of main pipe and valve: 15 to 50 (other ranges available as options) - Operation method: Manual operation and pneumatic operation methods are both applicable. *For more details, please refer to the catalog (P.20) or feel free to contact us. (An English version is available upon request!)*

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Tanks from approximately 10L to 10,000L are acceptable! The opening and closing is done solely by the diaphragm, allowing for smooth discharge of the tank contents with almost no residue left.

【Features】 ● The structure is directly welded to the bottom of the tank, providing excellent stirring efficiency. ● There are no contact parts such as gland packing, stem, seat, or gasket; the opening and closing are done solely by the diaphragm, allowing for smooth discharge of the tank contents with minimal residue. Contamination caused by valve components is extremely low, and cleaning and sterilization can be easily and reliably performed. ● The applicable nominal diameters range from DN15 to 100 (4S), making it suitable for use with small containers of about 10 liters to medium tanks of about 10,000 liters. 【Specifications (Excerpt)】 ● Main body material: SUS316L ● Applicable nominal diameter (DN): 15 to 100 ● Operation method: Manual operation and air-operated methods are both applicable. * For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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It is possible to manufacture valve bodies tailored to specific applications and specifications! "Bioclean diaphragm valves that are optimal for pharmaceutical bioprocesses and more."

This product is a valve suitable for manufacturing equipment in pharmaceuticals, bioprocesses, cosmetics, food, and semiconductors. The diaphragm completely isolates the fluid from the drive mechanism, providing a highly airtight structure. It has a packless design, eliminating the gland packing area that is typically associated with a high risk of leakage in standard valves, thus excelling in maintaining airtightness and preventing bacterial contamination. 【Features】 ■ Excellent airtightness ■ Structure that does not contaminate the fluid ■ Superior cleanability ■ Excellent maintainability ■ Customizable valve body according to application and specifications *For more details, please refer to the sanitary valve catalog (pages 8-16) or feel free to contact us. (English and Chinese versions are available upon request!)

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Prevent the generation of foreign substances due to coating peeling! Air-operated ON-OFF valve made of stainless steel with excellent corrosion resistance. Compact and buff-polished for excellent cleanability.

This product is an ideal valve for manufacturing equipment in pharmaceuticals, bioprocesses, cosmetics, food, and semiconductors. The air-operated ON-OFF valve is available in the stainless steel drive model 'BPO1400N type 05S to 16S'. Since painting is not required, it prevents the generation of foreign substances due to the peeling of the coating, and a retaining ring method is used to secure the bonnet and cylinder. With minimal unevenness and compact buff polishing, it excels in cleanability. 【Features】 ■ Made of all stainless steel with excellent corrosion resistance ■ Exterior shape with superior cleanability ■ Significant improvement in smooth operation and durability *For more details, please refer to the catalog (P15-16) or feel free to contact us. (English and Chinese versions are available upon request!)

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For pharmaceutical and food plants! A butterfly valve with minimal powder and particle adhesion and excellent cleanability.

The "Sanitary Butterfly Valve for Powder and Granule Discharge" has a proven track record for discharging powders and granules in pharmaceutical and food plants. The main components are made of stainless steel, and the inner surface is finished with #400 buff polishing, which minimizes the adhesion of powders and offers excellent cleanability. 【Features】 ■ Minimal adhesion of powders and excellent cleanability ■ Easy installation and removal for containers and piping ■ Adopts a clamp method for quick assembly and disassembly, making cleaning easy *For more details, please refer to the catalog or feel free to contact us.

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Rainproof equivalent to IP67! It has been transformed with an indicator that excels in visibility!

We would like to introduce our diaphragm valve limit switch box, the 'MDNB Series', designed specifically for air-operated drive units. The indicator of the conventional model has been changed from a rubber cap to a bright red dedicated resin indicator, improving visibility. This is a compact product with a direct mount type that incorporates a micro switch. 【Features】 ■ Direct mount type with built-in micro switch ■ Changed the indicator from a rubber cap to a bright red dedicated resin indicator ■ Improved visibility due to changes in cap shape *For more details, please refer to the PDF document or feel free to contact us.

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Introduction of lining products that prevent deterioration from corrosion and chemicals!

Introducing the "Lined Diaphragm Valve" with excellent resistance to corrosion and chemicals. It is utilized in a wide range of fields including chemicals, environmental and water treatment, pharmaceuticals, and semiconductors. It can be applied to countermeasure against corrosive fluids, gap corrosion, and metal ion elution. 【Product Lineup (Examples)】 "Type 430 Body": Hard natural rubber lining on a base material of FC200 or FCD-S "Type 459 Body": PFA lining on a base material of FCD-S or SCS13 "Type 460 Body": ETFE lining on a base material of FCD-S "Type 450 Body": Polyethylene lining on a base material of FC200 "Type 480 Body": Porcelain lining on a base material of FCD-S *Sanitary specification diaphragm valves are also available. *For more details, please refer to the catalog or feel free to contact us.

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Introduction of porcelain lining products with excellent resistance to corrosion and chemicals.

The "480(04) type" is a diaphragm valve made of porcelain lining that excels in corrosion and chemical resistance. It does not experience the permeation of chemical liquids, which can be a concern under certain conditions with fluororesin lining or rubber lining. Additionally, it is suitable not only as a corrosion-resistant valve for strong acidic fluids but also for highly permeable fluids such as hydrochloric acid and phosphorus trichloride. 【Features】 ■ Does not experience the permeation of chemical liquids, which can be a concern under certain conditions with fluororesin lining or rubber lining. ■ Suitable not only as a corrosion-resistant valve for strong acidic fluids but also for highly permeable fluids such as hydrochloric acid and phosphorus trichloride. ■ Base material: FCD-S, Lining: Porcelain *For more details, please refer to the PDF materials or feel free to contact us. (We have English and Chinese versions of the catalog available upon request!)

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Aiming to create environmentally friendly valves... "The entire company is united in promoting the continuous reduction of environmental impact!" "ISO 14001 certification obtained!"

Nihon Daiyavalve Co., Ltd. aims to be a sustainable company that balances environmental activities with economic activities as global environmental issues become more serious. We recognize our commitment to environmental conservation as one of the important pillars of our business activities and strive to fulfill our social responsibilities. In 2008, we obtained ISO 14001 certification and are working together as a company on environmental activities. *For more details, please refer to the PDF materials or feel free to contact us. (The English and Chinese versions of the catalog can be downloaded from the catalog page of the special website below.)

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In the field of food and health food research and development, an increasing number of companies are facing the following challenges: - Difficulty in exploring new functional materials and differentiation themes, leading to a depletion of research topics. - While they are collecting information from conferences and papers, they struggle to translate this into research themes directly related to their products. - They remain limited to competing similar products and follow-up projects, failing to establish uniqueness. - Although there are seeds of ideas, they struggle to elevate them to scientific hypotheses and build the necessary foundations for internal approval. Behind this lies a "wall of execution" that cannot be overcome by traditional information gathering and research processes. In this webinar, we will introduce a new R&D approach to break through these challenges. It is a next-generation research and development scheme that combines AI-driven hypothesis generation, which has achieved results in drug discovery, with scientific hypothesis verification by a food human trial CRO. This will allow for the transformation of vague ideas into scientifically verifiable projects, simultaneously achieving the construction of persuasive foundations for upper management and differentiation development.

Fujikohsuhou Industrial Co., Ltd. will hold an online seminar titled "Tips for Setting Laser Hardening Conditions" on July 20, 2025 (Wednesday). In laser hardening, factors such as output and speed are related to the quality of hardening. We will explain how output and speed are connected to quality factors. This seminar is aimed at those who are looking to start utilizing laser hardening. 【Recommended for】 ■ Those who want to learn about methods for setting laser hardening conditions ■ Those who want to obtain technical information about laser hardening

Take the 'first step' in DX talent development in Fukuoka. We will hold a free seminar where you can learn reskilling strategies that can be applied in the field through case studies and experiences! 'I've become responsible for DX, but I don't know where to start.' This is a participatory seminar aimed at representatives from small and medium-sized enterprises in Fukuoka City, Fukuoka Prefecture, where you can learn the 'first steps' in DX talent development and implementation support. While introducing case studies of representative DX tools such as Power Automate and Power BI, you will experience hands-on sessions with Copilot, allowing you to grasp practical small-start methods that can be implemented on-site. The content also includes specific success stories from the Fukuoka region, along with tips for promoting understanding and advancement within your organization.

We will be exhibiting at INCHEM TOKYO 2025, which will be held at Tokyo Big Sight from September 17 (Wednesday) to September 19 (Friday). This time, we will host many events, including special project stages and mini-seminars. At our booth, we will introduce our solutions and technologies based on the theme of "Sustainable Plant Engineering" from three different concepts. Please be sure to stop by our booth, East Hall 6, K-17.

The Siemens EDA Tech Forum is a technical event aimed at sharing the latest technological trends, case studies, and solutions to challenges with everyone involved in the design and development of silicon systems and electronic systems, while addressing evolving technologies, the densification and complexity of designs, and various design challenges, all while meeting requirements for quality, safety, and reliability. The goal is to deepen insights and networks towards achieving sustainable business. The forum covers a wide range of topics, from advanced design technologies and methods in fields such as 3D ICs, chiplets, chips for AI and ML (machine learning), and IC packaging, to the design, analysis, and collaborative development of electronic systems, including printed circuit boards, across multiple domains, as well as building ecosystems both internally and externally using digital threads. Through case presentations and explanations of design methods by industry leaders, it supports solutions to challenges faced in daily design work from all directions. This is a free technical event that requires pre-registration. We hope you will participate!